The film serves as Garrone's English-language debut and will interweave three separate story strands bookended by brief bits in which Italians Alba Rohrwacher and Massimo Ceccherini will play a street circus family. In one tale Salma Hayek will play a jealous queen who forfeits her husband's life. In another, Vincent Cassel plays a king whose passion is stoked by two mysterious sisters.
In 1977, paranormal investigators Ed and Lorraine Warren travel to London, England, where single mother Peggy Hodgson believes that something evil is in her home. When Peggy's youngest daughter starts showing signs of demonic possession, Ed and Lorraine attempt to help the besieged girl, only to find themselves targeted by the malicious spirits.
Sathya, an amateur police officer from Chennai is assigned to investigate strange supernatural incidents reported from a small village, Ayanpuram which had witnessed cruel governance during the British rule. On his arrival and over the course of the investigation, he falls for Viji, the beautiful daughter of the village headman. When Veera, a relative of Viji also seeks her hand, Sathya and Veera enter a challenge to stay inside the haunted 'Jackson' Bungalow for a week with the loser to give up his claim. The harrowing events they experience in the bungalow forms the rest of the story.
The sixteen year-old aspiring model Jesse arrives in Los Angeles expecting to be a successful model. The aspirant photographer Dean takes photos for her portfolio and dates her. Jesse befriends the lesbian makeup artist Ruby and then the envious models Gigi and Sarah in a party. Meanwhile the agency considers Jesse beautiful with a "thing" that makes her different and she is sent to the professional photographer Jack. Jesse attracts he attention of the industry and has a successful beginning of career. But Ruby, Gigi and Sarah are capable to do anything to get her "thing".
A squad of unsuspecting cops goes through a trapdoor to Hell when they stumble upon a Black Mass in an abandoned building.